Sean graduated from the University of Aberdeen; receiving hisM.Sc., Ph.D. in Clinical Pharmacology and D.Sc. in Science. He was a postdoctoral fellow at Lilly Research Laboratories, worked as a senior scientist at Pfizer and then Eli Lilly. He went on to become Associate Director of Computational Drug Discovery at Concurrent Pharmaceuticals Inc. and Vice President of Computational Biology at GeneGo. Sean is currently co-founder and CEO at Phoenix Nest Inc. focused on Sanfilippo Syndrome and Founder and CEO of Collaborations Pharmaceuticals, Inc. which uses machine learning approaches for rare and neglected disease drug discovery. He is also the on the SAB of the Pitt Hopkins Research Foundationand Adjunct Professor at 3 US universities. His work is NIH funded (NINDS, NCATS, NIAID, NIGMS). He has authored or co-authored >295 peer reviewed papers, book chapters, and edited 5 books on drug discovery research.